As is seen, the human genome project has its own flaws. Actually, at the beginning of the program, data analysis hasn’t gotten enough attention. In order to obtain adjacent sequence of each chromosome, the computer must splice thousands of individual sequence fragments (each about 100-300 kbp) together. Thus, it could be seen as a kind of new technical challenge during the calculation process.
In recent years, some genomics programs (such as the 1000 Genomes Project and the Cancer Genome Atlas Program) show how the policy program affects data generation to a large degree. Currently, US Precision Medicine Initiative is expected to get many unusual types of data, which will help to explore the best integration and analysis of these data, from electronic health records and genomic analysis to environmental monitor and body sensors.
As a priority to the development of modern technology, this project has made researchers realize a fact that they should take the tools and methods of genome sequencing and rendering maps as a larger project to develop. In fact, the project has spawned countless key genetics and triggered the innovation of subsequent molecular biology, chemistry, physics, robotics and computer science. At the same time, it also makes the use of tools and techniques of policy more creative. In recent cases, people prefer to connect a variety of incremental improvements together, enabling the revolutionary advances in scientific research (termicin), such as the DNA capillary sequencing equipment, which is eventually used to generate the first human genome.
Paying attention to technological innovation is extremely important in today’s large-scale projects, such as the Advancing Innovative Neurotechnologies Initiative, which aims to revolutionize common understanding on the human brain. In brief, the program is committed to develop the next generation tools that can identify all types of cells in brain and then record the various functions and behaviors of neural circuits on corresponding signal.
Nowadays, there are a lot of cutting-edge research ethics and social concerns, including the application concern of CRISPR/Cas9 gene editing tool, possible outbreak of infectious diseases, rapid treatment and design of clinical trials, etc. Unfortunately, a lot of team-based cooperation projects are not so successful as expected, even for the special bioethics research program. In fact, new large-scale program might play an effect on the ethical and social studies to a certain degree.
The goal of the Human Genome Project is quite bold. Given the fact that people do not know the results of human genome sequencing and analysis, someone is reasonable to hold skeptical attitude. Certainly, as long as the entire mission is based on a clear basis, quality standard and evaluation system, the project is likely to succeed. In addition, it still needs to repeatedly adjust the program updates.
In the career, scientists may witness to elucidate the molecular mechanisms in thousands of diseases, microbial genomics, mature cancer diagnosis and treatment, routine applications of stem cell therapy, as well as some other amazing medical achievements. It also reminds us that it’s significant to accept and welcome these technological changes.
No comments:
Post a Comment